Cerebrovascular Reactivity Remains Intact after Cortical Depolarization in Newborn Piglets
نویسندگان
چکیده
منابع مشابه
Cerebrovascular reactivity impairment after sport-induced concussion.
PURPOSE This study evaluated cerebrovascular reactivity (CVR) after a sport-induced concussion, also called mild traumatic brain injury (mTBI), by monitoring middle cerebral artery blood velocity (vMCA) with transcranial Doppler ultrasonography and simultaneous end-tidal carbon dioxide (PETCO(2)) measurements. METHODS Thirty-one athletes (16-25 yr old) participated in this study. The particip...
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Cerebrovascular reactivity to CO2 or hypotension was studied in vivo and in vitro [pressurized arteries (∼82 μm) and arterioles (∼30 μm)] at 1 h after mild controlled cortical impact (CCI) injury in rats. The cortical perfusion response [assessed using laser-Doppler flowmetry (LDF)] to altered CO2 was diminished (up to 81%) after mild CCI injury. The responses to CO2 alterations in arteries and...
متن کاملLimited role for nitric oxide in mediating cerebrovascular control of newborn piglets.
AIMS To investigate the effects of the nitric oxide (NO) synthase inhibitor L-nitro-arginine methyl ester (L-NAME) on cerebral blood flow, and its response to alterations in arterial carbon dioxide tension (CBF-CO2 reactivity). METHODS Cerebral blood flow was measured six times at varying arterial carbon dioxide tension (PaCO2) using the intravenous 133Xenon clearance technique in eight mecha...
متن کاملCerebrovascular reactivity and metabolism after subarachnoid hemorrhage in baboons.
Subarachnoid hemorrhage (SAH) was induced in baboons by puncturing the middle cerebral artery. Four to seven days later cerebral blood flow (CBF) responses to changing PaCO2 and to intracarotid infusion of 1.0, 2.5 and 5.0 micrograms of 5-hydroxytryptamine (5-HT)/kg/min were studied using the intracarotid 133xenon clearance technique. Indices of cerebral metabolism were determined by measuring ...
متن کاملوازوموتور راکتیویتی مغز(Cerebrovascular Reactivity) در حاملگی نرمال و پره‌اکلامپسی
Background & Aim: Preeclampsia is the major cause of maternal and perinatal morbidity and mortality. Transcranial Doppler(TCD) as a noninvasive procedure is used to assess hemodynamic changes in middle cerebral artery(MCA). Knowing the influence of normal pregnancy and preeclampsia on brain hemodynamics is essential for proper management of anesthesia, labor and vasoactive drug usage in the...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1999
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199906000-00009